Purdue University. "Environmental toxin may play important role in multiple sclerosis: Hypertension drug possible treatment."
ScienceDaily 23 November 2010. 25 November 2010 <http://www.sciencedaily.com
/releases/2010/11/101123174332.htm>.
Multiple Sclerosis or MS is a disease more often encountered at young adults and women; formed when myelin- a protective layer around nerves is damaged. As a result, the brain has difficulties “communicating” with other parts of the body. Acrolein on the other hand is a toxic air pollutant, being mostly found by tobacco and auto exhaust. Neuroscience professor Riyi Shi, at the Purdue University discovered that mice with multiple sclerosis have a 60% larger amount of acrolein in their spine. It basically eats away the connection the myelin has with the nerve. To my surprise, they seemed to may have found a way to solve this problem. It’s a hypertension medicine- hydralizine was proven to reduce the amount of acrolein, therefore delay MS. It is the first time this type of medicine seemed to have an effect on sclerosis, as well as the first time acrolein is proven to have such a drastic effect on myelin.
This article connects to our study of environmental issues and what they can cause. I never knew that pollution could go as far as sclerosis, a sickness that seemed so far from anything I thought it could cause. Now I’ve learnt what multiple sclerosis and acrolein are and how they impact each other. All I don’t understand is how a blood-pressure lowering medicine could help it. They seem to have nothing to do with each other. But now that I think of it, some things start making more sense. This disease is more often seen at young people, mostly because there isn’t anything to stop it; young people don’t usually need hypertension medicine. On the other hand, my and probably many other’s opinion on sclerosis was that only elders have it. This article completely changes our assumptions, and is completely shocking. It would be great if the medicine would work on humans the same way it does on mice, but won’t it be dangerous to take pills for something you don’t have. It’s like taking pills for stomach ache when you have a fever, then expecting it to work. I’m pretty sure we should test this more, and find out what exactly helps in hydralizine, then combine it with the old sclerosis pills and discover a revolutionary medicine.
This current event was easy to understand after some background information on what MS and acrolein are was researched. If you don’t know them before you read, you wouldn’t understand anything. The information was clearly valid, from a trustworthy website, with facts as well as the thoughts of the scientists. Before I started reading it I wondered what pollution has to do with brain damage and how do blood-pressure medicines help it.
I chose this article because of the many questions, doubts and opinions that popped up in my mind just by reading the title and the subheading. I’m very surprised and in the future, if they will ever manage to explain it, I would like to know how does the medicine really help as well as how are you supposed to know to take it if it only helps preventing multiple scoliosis?